UK-Peptides Review

UK-Peptides are setting the highest standards in the Research Peptide industry.

We are strongly confident that once you make your first purchase from UK-Peptides, you will never go anywhere else again. We have amazing feedback from our customers, and we always ask for honest reviews - you can see these at https://www.eroids.com/reviews/uk-peptides.com

if you require any more details about the science behind peptides we are happy to help, however we would emphasise that these products are for research use only

• Highest Quality Peptides -  USA made and 99% or higher purity  (complex peptides are 98%+) We will not supply anything less!
• Super Fast Order Processing - Guaranteed same day dispatch for all orders received by 4pm GMT. We use Royal Mail Special Delivery, next day guaranteed by 1pm
• Customer Service - Telephone, Social media & email sales support.
• We work directly with only the best and most reliable, long-term industry leading manufacturers.

Take a look for your self at http://www.uk-peptides.com you can always email us on Sales@uk-peptides.com

leave your reviews under this post

Epithalon (Epitalon) and Aging

Epithalon, also known as Epitalon is a synthetic peptide analog of epithalamin, a protein found in the pineal gland of mammals and of interest for its anti-aging properties. Past research studies have demonstrated that epithalamin can increase maximum life span in animals, decrease levels of free radicals, and alter catalase activity to prevent tissue damage [1]. Epithalamin has been shown to decrease mortality by 52% in fruit flies, by 52% in normal rats, and by 27% in mice prone to certain types of cancer and cardiovascular disease [2].

Epithalon has similar effects to epithalamin in mice and rats. It has also shown promise as an anti-cancer agent, reducing spontaneous mammary tumors in mice prone to them and reducing incidence of intestinal tumors in rodents. How does it achieve these effects?

Longevity 

Longevity isn't just about living longer, but about living healthier. Studies show that epithalon not only reactivates telomerase and thus extends a cell's life, but that it also reduces rates of DNA mutation, prevents degradation of immune function, promotes the health of the intestinal mucosa, and protects nerves from damage in rodent models [3]-[5]. In other words, epitalon extends both lifespan and health span (the number of years without disease or disability).

Mechanisms of Epithalon 

It isn't entirely clear how epithalon produces its wide-ranging effects. It does not influence standard mechanisms of longevity, such as calorie uptake or body weight. It does, however, seem to decrease the frequency of chromosome abberations in mouse models [6], [7]. Epithalon appears to be protective of DNA in more ways than one. It is clear that it activates telomerase and thus prevents the degradation of telomeres (the end caps of DNA strands), but it is less clear how epitalon prevents other types of DNA damage. At least some of the answer lies in its modulation of free radicals, but the mechanism is not sufficient to explain the far-reaching effects of epithalon. 

Research into the DNA protecting effects of epithalon is ongoing as are studies in mice regarding the long-term safety of using the peptide. Interestingly, epithalon appears to be more effective in decreasing the effects of aging in rodents. This fact may eventually help to track down the exact mechanisms by which epithalon works. 

Resources 

[1] V. N. Anisimov, S. V. Mylnikov, T. I. Oparina, and V. K. Khavinson, "Effect of melatonin and pineal peptide preparation epithalamin on life span and free radical oxidation in Drosophila melanogaster," Mech. Ageing Dev., vol. 97, no. 2, pp. 81-91, Aug. 1997.

Females and Peptides

Girls & Peptides Studies

This is a question that is often asked, but often left unexplained… or answered without evidence. To begin with there are a few factors that we need to look at to decide with peptides are best for females test subjects depending on goals.

THE GH PULSE.

Now all you guys out there, and even those of you unsure of your gender, you have 3 main pulses of gh released from the pituitary everyday, with your biggest at night.. hence the importance of not eating carbs as the blunt your gh release, and even more importantly avoiding fats for at least 90 minutes before bed, as Fats really blunt GH even more so than carbs.

You have a pulse in the morning, say if you went to bed at 10pm you would pulse around 6 am with your peak around 7am.

Then you have a pulse that’s normally the smallest of the 3 around 2-3pm, one of the reasons we often feel like sleepy or lethargic in the afternoon. We do have smaller surges in gh but often they release less than 13 μg.
Now a females release a nearly continuous amount of gh… where plasma levels are always elevated slightly above baseline levels of say 5 μg/day..

This release reminds us of the way in wich the peptide CJC-1295 with DAC works.
Hence the first peptide we will look at for female test subject use is the feminine cjc-1295 DAC.

CJC-1295 DAC. (GHRH)

DAC conjugated CJC 1295 (Receptor Grade) is an hGH secretogue that is unique by way of an additional lysine molecule that is added to facilitate the DAC complex. This conjugation makes for a much longer half-life, 8 Days.
During this time after 1 injection the release of gh reminds us of mountain with a gentle slope to the peak and a gentle slope back down the other side.. until reaching the normal pulsate of a female.
The cells within the pituitary release growth hormone in response to signalling by GHRH (Growth Hormone Releasing Hormone GHRH affects both the number of secreting cells and the amount they each secrete, wich is different from a GHRP (Growth hormone releasing peptide) As these are inhibited from releasing these stores by Somatostatin.

To give you an idea of its effectiveness a CJC-1295 pulsatility study performed on normal non-GH deficient people showed plasma levels were between 1 and 2 ng/ml or 1000-2000ng/L one week after injection of between 60 or 90 mcg/kg of CJC-1295.. thats a huge increase of baseline.
The other important factor is there are many kinds of gh released by the pituitary, and synthetic GH does not imitate the kinds released when you use a GHRH, healthier and better results are seen, especialy for females when using the extremely effective DAC version of CJC.. (DAC stands for Drug affinity complex)
So in quick summary, a female looking to imitate her own natural frequent mini pulses of gh would do well to use CJC-1295 DAC, as it imitates her own pulses.

But can you stack it and make it more effective… the quick answer is YES!! the long answer is as follows….

Enter the GHRP.

A GHRP such as GHRP-6 and Ghrelin has the ability to act on different populations of somatotropes (GH releasing cells). GHRP/Ghrelin increases the number of somatotropes releasing GH but not the amount released by each cell, which of course we’ve just seen CJC 1295 -DAC can do.
So they make a great team, increasing the amount of cells that release GH, then increasing the amount of GH released by these cells…

GHRP-6, is a polypeptide hormone, and a growth hormone secretagogue and ghrelin mimetic and analog. GHRP-6 is from the first generation of GHRPs and causes significant release of growth hormone by itself, due both to its suppression of somatostatin (an antagonist to GHRH) and stimulation of release of GH from the anterior pituitary. It does increase cortisol but not as significantly as say Hexarelin, it does though increase hunger and sadly unlike Ghrelin doesnt cause fat loss… not on its own, but only through GH release…but used in moderation with CJC-1295 DAC as above the results can be outstanding, seeing a marked increase in GH release, and the benefits that go along with that, of fat loss, improved skin tone, muscle tone, muscle recovery, even improved liver function, and increased igf levels leading to increased muscle growth, as well as helping any existing injuries by protecting tendons and joints.

BPC-157 (HEALING PEPTIDE) Dosage

BPC-157 is known for super quick and professional Joint/tendon/ligament healing in all phases of clinical trials. BPC-157 has been shown in studies to heal torn quadriceps muscles, detached achilles tendon, muscles that have been damaged/crushed. Demonstrating dramatic fast recovery from muscle tears. Tendon to bone healing – increased ligament healing, BPC-157 has a variety of protective effects in the organs.

BPC 157 peptide has been shown to heal a variety of wounds in all areas researched, including internal organs, muscles, ligaments, tendons, skin, internal lacerations from surgery, etc

BPC-157 Dose:

200mcg being a medium dose up to 500mcg Depending on severity of issue (if severe) dose 2x a day at 350 mcg totaling 700 mcg.

How to take Sublingual or injected:

BPC 157 is both, you can do IM or subq as close as you can to the injection site, preferably around 1-4 inches away to yield the most benefit to the injured area

Duration:
BPC-157 can be run for 4 weeks, followed by a 2 week rest. after this if you are still not feeling 100% itll be safe to run another course of BPC-157.

Dilution:
Gently alcohol swab the stopper, then let it dry, same goes with the BAC water vial. Dose out the correct amount of BAC water. Slowly put the needle in… then slowly but surely inject the BAC water along side the vial making sure you do not indirectly inject on the peptide powder.

Note* this is done with 2mls of bac water, that would be 2 whole 1ml/1cc insulin syringes.

Stacked:
thymosin beta 4

Storage:
Keep away from UV/sunlight. It can stay in room temp for up to 10 weeks, however for best storage/results store in a fridge and use until vial is run out then discard of. For other BPC 157, they can stay in the fridge too as they’ll last up to 6 months, whereas if you had more you can store in the freezer (up to 2 years).

Selank Dosage & Benefits

Selank

Selank is one of the newer substances to hit the market in recent years. It is considered to be heptapeptide and an accessory drug or substancewhich has anxiolytic (anti-anxiety) effects. This supplement was developed at the Institute of Molecular Genetics of the Russian Academy of Science. There is quite a buzz about this new drug for a number of potential benefits that could have a wide range of applications and uses. At the present time, Selank has completed stage III clinical trials in Russia and is awaiting the go-ahead for release to human use.

Selank Benefits:
One of the first benefits most users will be able to see with Selank is a stabilization and improvement in their overall mood. It leads to feelings of contentment and well-being. What is even more interesting is that this effect is not sedating, but rather calming. At the same time, most users are able to feel improved mental clarity and overall enhanced cognitive function.
Anyone who is suffering from the condition known as anhedonia may benefit from this nootropic agent. Anhedonia is a condition where someone is not able to experience pleasure. This is often created through the use of amphetamines or other opioid type drugs which play with the workings of the brain’s pleasure center. Selank has been shown to help restore the proper functioning of this are of the brain, although it should only be considered as one part of a broader treatment plan.
From a purely Nootropic point of view, there are additional benefits as well. This includes helping to reduce anxiety in a number of different forms such as generalized anxiety disorder, social anxiety disorder, and even Panic Disorder. It also improves the ability to focus and concentrate, increase mental sharpness, reduce mental fatigue, increase memory and learning capacity, and even improve cognitive functioning when in a sleep deficit.

Selank Dosage:
The generally accepted daily dosage range is anywhere from between 250 mcg to 3 mg. Of course, you should always start with the lowest effective dose and then work your way up, if needed at all, in a very thoughtful, slow, and controlled fashion. It is also thought that this supplement is very benign and that doses even up to 500 times that of the effective range have been shown to be well tolerated by the human body.

Selank Side Effects:
Since this drug is very well-tolerated and considered generally safe, there are not many side effects to report. In fact, there are no significant side effects to report, along with no allergic reactions, interactions, or even addiction or withdrawal potential. That being said, drugs will affect people in different ways and caution is always necessary. It should also be mentioned that this is a newer compound with a shorter history of use. Future research may uncover risk factors that are not known today.